Postdoc position in physiology - Scholarships
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Postdoc position in physiology – Scholarships

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Postdoc place in physiology – Scholarships

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Venture title:  Postdoc place in bivalve and crustacean physiology / vitamin / neuroendocrinology

Topic space

Molecular Biology / Metagenomics / Biochemistry / Physiology

Key phrases

Bivalve, crustacean, neuroendocrine operate, microbial relationships, nutritional vitamins, metabolomics, proteomics

Job description

We’re looking for a candidate for a postdoc place, length 17 months, to work within the common space of bivalve physiology and neuroendocrinology. A number of attainable tangents could be pursued relying on the pursuits of the candidate and their background/expertise.

The primary attainable angle could possibly be in hint mineral / vitamin metabolic pathways in key business species of bivalve mollusks. As in human vitamin, nutritional vitamins and minerals are wanted by mollusks and crustaceans for progress and survival. Relative to macronutrients, these micronutrients are required in scant quantities relative to gross consumption, however are essential for key metabolic processes. In livestock and finfish aquaculture manufacturing, micronutrient necessities for each nutritional vitamins and minerals are largely recognized, thus permitting for feed formulations designed to optimize manufacturing values primarily based on recognized nutrient compositions. Key vitamin and mineral necessities for a lot of mollusk and crustacean species will not be comparatively properly researched, regardless of the numerous affect of micronutrients on metabolic exercise, progress and survival, particularly throughout early growth phases. Thus, we suggest a collection of experiments working straight with vitamin B12, taurine and zinc metabolism in key business mollusk and crustacean species.

A second focus of the place, with the identical funded mission, could possibly be on neuroendocrinology of bivalve mollusks. Surprisingly little can also be recognized in regards to the nature of neuroendocrine operate in mollusks, even supposing many neuroendocrine compounds, together with serotonin, catecholamines and estrogenic compounds that regulate replica in people are additionally present in bivalve mollusks. Catecholamines reminiscent of epinephrine are routinely utilized in aquaculture hatcheries to induce metamorphosis in lots of bivalve mollusk species, however little is understood in regards to the pathways of motion or the hormonal occasions previous this stage of growth, together with gametogenesis and spawning.

Neurohormones regulate the physiology in all increased eukaryotes, however lately, anthropogenic sources of endocrine disrupting compounds (EDCs) within the marine setting from wastewater discharge, industrial contaminants and agriculture have turn out to be critical considerations as they disrupt reproductive physiology in a variety of marine organisms. As mollusks are key species in marine ecosystems, large-scale breeding failures as a consequence of pollution have cascading results on marine ecosystems.

Though mammalian and fish intercourse hormones have been comparatively well-studied, the function of hormones in mollusks is an rising area, the place latest breakthroughs in genetic and molecular strategies supply the potential for thrilling new discoveries. The aquaculture trade as an illustration may be very desirous about gaining a greater understanding of bivalve endocrinology as a way to predict, and even management, the intercourse ratio of breeding populations, as rising egg manufacturing or the power to pick out for intercourse can tremendously enhance productiveness. A greater data of hormonal pathways in mollusks, as an illustration, can present hatcheries with higher management over the timing of sexual maturation, assist synchronize fertilization or enhance survival throughout metamorphosis.

The place might contain work with key species of economic mollusks to:

  • The function of particular EDCs and their interference with functioning of the reproductive system, reminiscent of irregular gonad construction and differentiation, intersexuality and intercourse reversal;
  • Chemical and bodily strategies for inducing synchronized feminine gonad growth and egg launch primarily based on particular endogenous compounds recognized to be related to feminine gamete maturation in different invertebrate species;
  • Neurohormonal pathways controlling settlement and metamorphosis to help in selective breeding and hatchery manufacturing of larval cohorts.

Key {qualifications}

We’re looking for a candidate who’s unbiased and self-motivated. At minimal, the candidate should possess an PhD in molecular biology, cell biology, physiology or associated disciplines. Prior background in business bivalve aquaculture, together with conditioning and feed manufacturing, in addition to experimental work in bivalve physiology, fish vitamin / eco-toxicology or neuroendocrinology is fascinating. Expertise in a single or a number of of the next methodologies can be advantageous: histology, mild and epifluorescence microscopy, molecular biology (PCR, cloning, quantitative PCR, RNAseq, microbiome evaluation), proteomics, genomics, bioinformatics, biochemistry, analytical chemistry (together with chromatography strategies reminiscent of HPLC / GC), stream cytometry. Additional expertise might embody confocal, multi-photon, super-resolution and/or electron microscopy. Data with immunohistochemistry or immunocytochemistry can also be related, as is cell tradition work (main and cell traces) and different cell signaling/cell organic strategies. It isn’t a requirement that the candidate has prior expertise in aquaculture, however it might be advantageous to have expertise reminiscent of technical operation of multiphase bioreactors and/or aquaculture or aquaria methods. Expertise with numerous strategies in microbiology, molecular biology, bioanalytical assays and dealing with different microorganisms (e.g. fungi, cyanobacteria, viruses) are thought-about deserves.

The main points of the mission could be adjusted primarily based on the candidate’s expertise and pursuits. The place can even permit for a mixture of analysis (85%) with (if desired) dissemination and administration actions (15%).  Below such circumstances, the profitable candidate would want to develop their very own analysis instructions and conduct their very own experimental/analysis work whereas additionally supporting the Principal Investigator with the general configuration of the mission, which would come with duties reminiscent of: (i) managing net content material (writing/designing/ updating net pages); net and movie video/movie enhancing; (ii) creating clear, compelling knowledgeable written and verbal communications, together with experiences; (iii) helping different workers throughout the analysis workforce to prepare workshops and mission conferences and talk analysis outcomes via numerous dissemination channels. Actual job description could be negotiated previous to the beginning date primarily based on the candidate’s expertise and pursuits.

Private {qualifications}

The place is predicated on the College of Gothenburg, Sweden. The place additionally entails frequent worldwide journey because the work is being conducting with a number of worldwide laboratories and trade companions. The candidate can be chargeable for operating utilized experiments in a number of completely different labs (Europe, Australia, Southeast Asia) thus requiring flexibility for prolonged stays in numerous areas in addition to frequent worldwide journey to take part in conferences, working teams, conferences and visits with trade companions. The candidate should subsequently exhibit a willingness and skill to work for prolonged intervals in several nations. The candidate may even assist host visiting researchers from these international labs in Sweden. Candidates with none prior worldwide work/examine expertise is not going to be thought-about.

Glorious communication expertise (written and spoken) in English are crucial, however the candidate doesn’t want Swedish or EU citizenship, as residence permits can be organized for the profitable candidate.

Software process

To be able to apply for a place on the College of Gothenburg, you need to register an account in our on-line recruitment system. It’s the accountability of the applicant to make sure that the appliance is full in accordance with the directions within the job commercial, and that it’s submitted earlier than the deadline.

The appliance should embody:

  • A CV and canopy letter that describes how the applicant meets the choice standards
  • Proof of sturdy tutorial writing expertise (please present 3 first creator peer-reviewed manuscripts, any experiences, and a replica of the PhD thesis)
  • Identify and get in touch with particulars of three referees connected in a file entitled References your title.pdf

If the next gadgets will not be evident on the CV, please state clearly within the cowl letter the way you meet the next necessities:

  • Proof of analysis and scientific writing expertise with at minimal 3 revealed articles as first creator in a peer-reviewed journal (please additionally spotlight any technical experiences written). Full-text of three articles and PhD thesis should be supplied with the appliance;
  • Willingness to journey internationally for analysis, conferences and different mission conferences;
  • Demonstrated statistical expertise, together with software program reminiscent of R.

Rules for the analysis of {qualifications} for tutorial positions are given in Chapter 4, Part 3 – 4 of the Larger Training Ordinance.

Totally Funded Scholarships for Worldwide College students to Work and Examine Overseas

Employment phrases

First day of employment: By settlement

The precise begin date for this place is negotiable relying on the supply of an acceptable candidate. The guy can be employed for an preliminary one-year interval to guide this mission with the likelihood for renewal. You’ll have a full spectrum of trip and journey advantages, in addition to protection from nationwide well being and enterprise journey insurance coverage.

Contact info

For additional details about the place, please contact Alyssa Joyce: alyssa.joyce@gu.se

Deadline of place:  October 31, 2021

In connection to this recruitment, we have now already determined which recruitment channels we must always use. We subsequently decline additional contact with distributors, recruitment and staffing firms.

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