PhD fellowship in Epitranscriptomics and cancer at the Department of Cellular and Molecular Medicine
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PhD fellowship in Epitranscriptomics and cancer at the Department of Cellular and Molecular Medicine

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PhD fellowship in Epitranscriptomics and most cancers on the Division of Mobile and Molecular Medication

A PhD place is obtainable on the Division of Mobile and Molecular Medication (ICMM) School of Heath Sciences (SUND), College of Copenhagen within the H. Nielsen Group headed by Professor Henrik Nielsen. The place begins 1 January 2022 and extremely motivated and dedicated candidates with an curiosity in most cancers and RNA biology are inspired to use.

The challenge is totally funded by the Danish Most cancers Society however the PhD fellow can be inspired to hunt a private funding to assist their PhD stipend.

Our group and analysis
The H Nielsen group is embedded on the Division of Mobile and Molecular Medication (https://icmm.ku.dk/english/). The group makes a speciality of RNA biology with emphasis on catalytic RNA and RNA modifications in ribosomal and spliceosomal RNA. Most initiatives are carried out in collaboration with worldwide analysis companions.

Mission description
On this challenge, we emphasize the function of RNA-guided RNA-modifications, akin to ribose methylation and pseudouridylation of ribosomal RNA and the way these modification impression translation in regular cells and in most cancers. The challenge builds on current publications from the group demonstrating pronounced perturbations of the RNA modification sample in most cancers cell strains and affected person samples in addition to detailed molecular analyses of the impression of particular person modifications on the interpretation course of. The precise purpose is to ascertain the connection between expression of information RNAs, the instalment of nucleotide modifications and the implications on the degree of mRNA recruitment and translation for chosen websites of explicit relevance in most cancers. The challenge is a collaborative effort with medical analysis teams to make sure its relevance to medical practise.

Begin:                                  1 January 2022
Period:                           3 years as a PhD pupil
Working hours:                 37 working hours per week in common.

Job description
Your key duties as a PhD pupil at SUND are:

  • Carry by way of an unbiased analysis challenge beneath supervision.
  • Full PhD programs or different equal training comparable to approx. 30 ECTS factors.
  • Take part in lively analysis environments.
  • Receive expertise with educating or different varieties of dissemination associated to your PhD challenge
  • Write a PhD thesis on the grounds of your challenge.

There will even be a research-based educating within the ICMM curriculum, together with at undergraduate degree.

Profile
We’re on the lookout for a extremely motivated and enthusiastic particular person with the next competences and expertise:

  • Should maintain a Grasp’s diploma in a associated space of molecular biology, cell biology or biochemistry.
  • Should present proof of publication-standard analysis, preferable throughout the areas of human molecular and cell biology, RNA biology or most cancers.
  • Sturdy communication and collaboration expertise, together with the power to work properly in a global educational setting.
  • Potential to work in a workforce of multidisciplinary scientists, and the potential to work independently with restricted course.
  • Wonderful written and oral communication expertise in English.

Key standards for the evaluation of candidates
Candidates should have {qualifications} comparable to a grasp’s diploma associated to the topic space of the challenge e.g. biochemistry, molecular biology, biology or cell biology.

As a prerequisite for a PhD fellowship employment, your grasp’s diploma should be equal to a Danish grasp’s diploma. We encourage you to learn extra within the evaluation database: https://ufm.dk/en/training/recognition-and-transparency/find-assessments/assessment-database. Please word that we’d ask you to acquire an evaluation of your training carried out by the Ministry of Larger Training and Science

Different essential standards are:

  • Skilled {qualifications} related to the PhD programme.
  • Earlier publications.
  • Related work expertise in most cancers biology, RNA and cell biology.
  • Different skilled actions.
  • Curious mind-set with a powerful curiosity in most cancers and RNA biology.
  • Private drive and dedication to science.
  • Wonderful English language expertise.

Place of employment
The place of employment is at Division of Mobile and Molecular Medication, Panum Institute, College of Copenhagen. We provide artistic and stimulating working situations in a dynamic and worldwide analysis atmosphere. Our analysis amenities are inside trendy laboratories together with devoted cell and isotope labs.

Phrases of employment and employment
The employment as a PhD fellow is full time (37 working hours per week) and for 3 years.

The place is conditional upon the candidate’s profitable enrolment within the PhD faculty on the School of Well being and Medical Sciences, College of Copenhagen. This requires submission and acceptance of an software for the precise challenge formulated by the candidate in session with the supervisors.

The PhD research should be accomplished in accordance with The Ministerial Order on the PhD programme (2013) and the school’s guidelines on reaching the diploma. Wage, pension and phrases of employment are in accordance with the agree­ment between the Ministry of Finance and The Danish Confederation of Skilled Associations on Lecturers within the State.
Relying on seniority, the month-to-month wage begins at DKK 27,778 / approx. EUR 3,730 (April 2021-level) plus an employer paid pension contribution at 17.1 %.

Questions
For particular details about the PhD fellowship, please contact principal supervisor professor Henrik Nielsen by e-mail: hamra@sund.ku.dk.

Basic details about PhD applications on the School of Well being and Medical Sciences is obtainable on the Graduate Faculty’s web site: https://healthsciences.ku.dk/phd/.

Utility process
Your software should be submitted electronically by clicking “Apply now”.
The appliance should embrace the next paperwork in PDF format:

  1. Motivated letter of software (max. one web page).
  2. CV incl. training, expertise, language expertise and different expertise related for the place.
  3. Licensed copy of authentic Grasp of Science diploma and transcript of information within the authentic language, together with a certified English translation if issued in different language than English or Danish. Grasp’s diploma should be equal to a Danish grasp’s diploma. If not accomplished, a licensed/signed copy of a current transcript of information
  4. Record of publications (if attainable).

Utility deadline: 15 October 2021, 23.59 p.m. CET.

We reserve the proper to not take into account materials acquired after the deadline, and to not take into account functions that don’t stay as much as the abovementioned necessities.

The additional course of
After the expiry of the deadline for functions, the licensed recruitment supervisor selects candidates for evaluation on the recommendation of the hiring committee. All candidates are then instantly notified whether or not their software has been handed for evaluation by an unbiased assessor.

The assessor makes a non-prioritized evaluation of the tutorial {qualifications} and expertise with respect to the above-mentioned space of analysis, strategies, expertise and different necessities listed within the commercial.

As soon as the evaluation work has been accomplished, every applicant has the chance to touch upon the a part of the evaluation that pertains to the applicant him/herself.

The School of Well being and Medical Sciences contains roughly 8,000 college students, 1,790 PhD college students and 5,100 workers. The School advances the sector of well being sciences by way of its core actions: analysis, educating, data sharing and communication. With fundamental analysis fields starting from molecular research to research of society, the School contributes to a wholesome future by way of its graduates, analysis findings and innovations benefitting sufferers and the group. The College of Copenhagen needs to mirror the encompassing group and invitations all no matter private background to use for the place

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A part of the Worldwide Alliance of Analysis Universities (IARU), and amongst Europe’s top-ranking universities, the College of Copenhagen promotes analysis and educating of the very best worldwide commonplace. Wealthy in custom and trendy in outlook, the College provides college students and workers the chance to domesticate their expertise in an bold and casual atmosphere. An efficient organisation – with good working situations and a collaborative work tradition – creates the perfect framework for a profitable educational profession.

Contact

Henrik NielsenE-mail: Hamra@sund.ku.dk

Information

Utility deadline: 15-10-2021Employment begin: 01-01-2022Working hours: Full timeDivision/Location: Division of Mobile and Molecular Medication

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