Doctoral student in Clinical Neurochemistry
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Doctoral student in Clinical Neurochemistry

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Doctoral pupil in Medical Neurochemistry

The College of Gothenburg tackles society’s challenges with numerous data. 53 500 college students and 6 500 workers make the college a big and provoking place to work and research. Robust analysis and enticing research programmes appeal to scientists and college students from all over the world. With new data and new views, the College contributes to a greater future.

The Division of Psychiatry and Neurochemistry is situated on the Institute of Neuroscience and Physiology on the School of Well being Care Sciences at Sahlgrenska Academy, College of Gothenburg. On the Division analysis is performed on human behaviour, neuropsychiatric processes in addition to psychiatric remedy and analysis in shut collaboration with Västra Götaland area and various worldwide companions. We take part within the undergraduate programmes in Medication and inside The Nationwide Analysis College in Psychiatry/Southwest Sweden. On the Division there are some 15 analysis teams and 4 analysis facilities.

Undertaking title: Biomarkers for neurodegenerative ailments – the MIRIADE undertaking

Job assignments

The PhD training in Medical Science contains finishing up a scientific undertaking and finishing not less than 30 credit of programs at third-cycle degree. The doctoral pupil should additionally write a scientific compilation thesis or monograph comparable to not less than 120 credit. For extra details about third-cycle research at Sahlgrenska Academy, see https://www.gu.se/en/sahlgrenska-akademin/doctoral-studies

The undertaking is being pursued within the framework of the Marie Skłodowska-Curie Revolutionary Coaching Community miriade.eu (Multi‐omics Interdisciplinary Analysis Integration to Handle DEmentia analysis). The overarching purpose of the MIRIADE undertaking is to coach a novel technology of scientists in a position to speed up dementia biomarker growth. MIRIADE contains of ten world-leading analysis organisations, 5 small to massive industries and a couple of sufferers organisations, from 12 nations within the EU, South-Korea and USA. A complete of 15 Early Stage Researchers (ESRs) might be hosted throughout the community. The undertaking will leverage present proteomics datasets to establish essentially the most promising candidate biomarkers for the most important types of dementias. It is going to develop an overtly accessible built-in information platform for biomarker growth (ESR1). ESR undertaking 2 will deal with the prediction of protein-antibody interactions success in biomarker assay growth. ESR3 will characterise protein floor accessiblility states in particular organic matrices, to enhance biomarker assay growth. ESR4-6 will develop particular response monitoring assays and validate these in CSF and blood of sufferers with AD (ESR4), FTD (ESR5) or DLB(ESR6). ESR7-10 will develop novel immunoassays in CSF and blood for all dementias (ESR7); AD (ESR8), FTD (ESR9) or DLB (ESR10). ESR11 and 12 will deal with the market-ready growth of plasma abeta42 and abeta40 assays (ESR11) or neurofilament gentle (ESR12). ESR13 will develop reference strategies for SRM assays for amyloid and neurofilament gentle CSF and blood assays. ESR14 and 15 will deal with innovation of the method, with a purpose to generate a roadmap for environment friendly biomarker growth. ESR14 will research how information are organized, shared, reused and built-in in academia and ESR15 will evaluate and consider completely different workflows of biomarker growth.

The purpose of WP2, the place the present PhD pupil would work, is to generate assays for the candidate biomarkers chosen in WP1, that are widespread and particular for every dementia kind. Biomarker assays in CSF and blood might be developed utilizing state-of-the-art protein applied sciences (e.g., Simoa, focused mass spectrometry). Calibrators and qc might be developed. The identical biomarkers might be developed on completely different applied sciences, for optimum synergism and comparability of the efficacies of every technique to construct a roadmap for optimised growth in WP5. There might be steady interplay of WP2 with WP1 and among the many ESRs in WP2 for collection of biomarkers and reagents (e.g., antibody prediction analysis, use antibodies to extend SRM sensitivity).

Third-cycle research are equal to 4 yr full-time and result in a Diploma of Physician. These appointed to doctoral studentships shall primarily dedicate themselves to their research. These appointed to doctoral studentships could, nevertheless, work to a restricted extent with academic duties, analysis and administration (departmental duties). Earlier than a PhD diploma has been awarded, duties of this sort could not comprise greater than 20 per cent of a full-time put up.

Eligibility

To be eligible for third-cycle research, the applicant should meet each the overall and particular entry necessities.

An individual meets the overall entry necessities for third-cycle research if she or he:
1. has been awarded a second-cycle qualification
2. has glad the necessities for programs comprising not less than 240 credit of which not less than 60 credit had been awarded within the second-cycle, or
3. has acquired considerably equal data in another manner in Sweden or overseas

An individual meets the particular entry necessities for third-cycle research in Medical Science if she or he has efficiently accomplished the English B/6 course or is taken into account to have acquired equal data via earlier research

Evaluation

In deciding on between candidates who meet the overall and particular entry necessities, their skill to learn from third-cycle research shall be taken into consideration. The evaluation shall connect explicit significance to documented {qualifications} for:
– particular data and expertise inside the topic space and associated analysis fields
– expertise of scientific principle and related analysis methodology
– scientific evaluation and presentation verified via thesis, diploma undertaking, scientific journals or the like.

Documented expertise of laboratory work with biomarker assays (e.g., ELISA) related for the undertaking is of benefit. A robust dedication for science and powerful motivation to conduct a PhD training, a robust private drive and good collaboration expertise is very fascinating. Private suitability is of nice significance.

Employment

After admission to third-cycle research you’ll be appointed to doctoral studentship. Laws for employment of doctoral college students are given in SFS 1993:100. The preliminary appointment could apply for not than one yr. An appointment could also be renewed for not more than two years at a time. An individual could also be appointed to a doctoral studentship for a complete of eight years. The overall employment interval could, nevertheless, not exceed the time comparable to full-time third-cycle research for 4 years.

Location: Sahlgrenska Academy, Institute of Neuroscience and Physiology, Division of Psychiatry and Neurochemistry. Extent: 100%. First day of employment: as agreed. MSCA employment in a Marie Sklodowska Curie Program with MSCA financing.

Salaries for doctoral college students are regulated in a neighborhood settlement on the College.

Extra info

In an effort to be accepted for MSCA financing the applicant, on the time for the appliance, shouldn’t have resided in Sweden greater than 12 months within the 3 years instantly previous to the reference date. Furthermore the applicant have to be within the first 4 years (full-time equal analysis expertise) of their analysis careers and haven’t been awarded a doctoral diploma.

For additional info relating to the place

For extra details about the undertaking please contact the supervisors:

Ulf Andreasson, Affiliate Professor, Institute of Neuroscience and Physiology,
e-mail: ulf.andreasson@neuro.gu.se

Henrik Zetterberg, Professor, Institute of Neuroscience and Physiology,
telephone: +46 768 672647, e-mail: henrik.zetterberg@neuro.gu.se

Unions

Union representatives on the College of Gothenburg:
https://www.gu.se/en/about-the-university/work-at-the-university-of-gothenburg/how-to-apply

Info for Worldwide Candidates

Selecting a profession in another country is an enormous step. Thus, to provide you a basic thought of what we and Gothenburg have to supply by way of advantages and life usually for you and your loved ones/partner/associate please go to:

https://www.gu.se/en/about-the-university/welcome-services

https://www.movetogothenburg.com/

Totally Funded Scholarships for Worldwide College students to Work and Research Overseas

apply

In an effort to apply for a place on the College of Gothenburg, it’s a must to register an account in our on-line recruitment system. It’s the duty of the applicant to make sure that the appliance is full in accordance with the directions within the job commercial, and that it’s submitted earlier than the deadline.

It’s essential to embrace the next, in pdf format

  • Private letter
  • CV
  • Diploma and transcripts displaying that you simply meet with the overall entry requirement
  • Proof of completion of  English 6 course or the acquired equal data via earlier research

In case your diploma is from a college outdoors of Sweden, just remember to connect a diploma and full transcripts that makes assessing your diploma simpler

In case your diploma has not been verified by a Swedish authority it’s good to present contact particulars to the issuing college, registrar or comparable, that may confirm the diploma at our request.

For info on what it’s good to submit with a purpose to fulfill the English language requirement see https://www.universityadmissions.se/en/entry-requirements/english-language-requirements/

Deadline: 2021-10-18

The College of Gothenburg promotes equal alternatives, equality and variety.

Functions might be destroyed or returned (upon request) two years after the choice of employment has turn into ultimate. Functions from the employed and from those that attraction the choice won’t be returned.

In connection to this recruitment, we now have already determined which recruitment channels we should always use. We due to this fact decline additional contact with distributors, recruitment and staffing corporations.

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